Ionis Pharmaceuticals, Inc.
Get verified emails for Ionis Pharmaceuticals, Inc. employeesAbout Ionis Pharmaceuticals, Inc.
Founded in 1989 and based in Carlsbad, California, Ionis Pharmaceuticals, Inc. develops medicines for serious diseases. The company is known for pioneering RNA-targeted medicines and also advances new approaches in gene editing.
Ionis has five marketed medicines and a pipeline that includes programs in neurology, cardiology, and other areas of high patient need. Its work is driven by disease biology and technology focused on RNA therapies.
The company employs 501-1000 people. Over three decades, Ionis has built its business around discovering and developing medicines intended to address significant unmet medical needs.
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Insights
Updated 31 Aug 2026Ionis Pharmaceuticals appears to be competing on clinical differentiation in severe hypertriglyceridemia. SHASTA-3 and SHASTA-4 found that plozasiran cut triglycerides by roughly 80% and acute pancreatitis events by 78%. That is the clearest competitive signal in the supplied sources.
Its strategic direction in these sources centers on advancing a therapy for a high-need cardiometabolic setting. The reported reductions in triglycerides and pancreatitis events point to a focus on outcomes that matter clinically as well as commercially.
Investor sentiment in the supplied materials looks constructive. Multiple institutional investors opened new positions in Ionis during the second quarter, including The Manufacturers Life Insurance Company, Corient Private Wealth LP, and North Star Asset Management, which suggests continued interest from professional capital.
Frequently asked questions
Ionis Pharmaceuticals, Inc. is headquartered in Carlsbad, California, United States.
Ionis Pharmaceuticals, Inc. has 501-1000 employees according to its company profile.
Ionis Pharmaceuticals, Inc. operates in the Biotechnology sector. Public valuation figures are not always disclosed for private companies.